Janssen Research & Development, a division of Johnson & Johnson's Family of Companies is recruiting for a Senior Scientist, Toxicology located in Beerse, BE.
At the Janssen Pharmaceutical Companies of Johnson & Johnson, we are working to create a world without disease. Transforming lives by finding new and better ways to prevent, intercept, treat and cure disease inspires us. We bring together the best minds and pursue the most promising science. We are Janssen. We collaborate with the world for the health of everyone in it. Learn more at www.janssen.com and follow us @JanssenGlobal.
This Senior Scientist in Global Toxicology, a department in the Preclinical Science and Translational Safety (PSTS) organization within Janssen Research & Development supports nonclinical safety evaluation in late discovery and development for various therapeutic areas.
Essential Functions:
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- Design of in vivo general toxicology studies for biologics, small molecules, gene therapies, RNAs, and vaccines; integrated scientific data interpretation and report generation;, and close collaboration with nonclinical project representatives.
- Oversee and monitor contracted in vivo toxicology studies in compliance with Good Laboratory Practices (GLPs).
- Conduct in-house studies according to the guidelines of the various Health Authorities and in compliance with Discovery Data Integrity (DDI) principles.
- Serve as subject matter expert based on individual expertise/experience
- Engagement in multi-disciplinary teams within PSTS to provide scientific and technical expertise on drug development programs.
- Participate on issue-resolution teams through active engagement in scientific discussions and the shaping of strategies designed to support and inform critical development decisions.
- Provide strong scientific input regarding potential mechanisms of toxicity in molecular pathways and propose appropriate follow-up. Maintain up-to-date knowledge regarding innovative approaches in toxicological research.
- Work independently, foster constructive cross-functional collaborations with both internal and external partners, and be able to prioritize work load in alignment with pipeline priorities.
- The candidate will contribute to the success and growth of PSTS through active participation in internal and external committees / working groups and will closely interact with scientists in other functional areas including Pathology; Bioanalysis; Toxicokinetics; and development project leaders in the US, Belgium, and China.
Qualifications
- A Master’s degree in Biomedical Sciences, Toxicology, or similar education with at least 5 years of experience in Pharmaceutical/Biopharm industry or a DVM or PhD in Toxicology, pharmacology or related life science with at least 2 years of relevant experience.
- Experience as a Study Director, Toxicologist, or Study Monitor conducting/overseeing in vivo toxicology studies supporting projects in discovery through development is required
- Knowledge of major species typically evaluated as toxicology models is required
- Strong written and verbal communication skills and the ability to negotiate and influence decision-making processes, think and manage issues to resolution, and contribute to study teams and scientific discussions are required with prior experience in scientific data evaluation, integrated safety assessment, and scientific writing
- Capable of making fast decisions when necessary, while maintaining positive and inclusive team relationships, is required
- Personal leadership skills, a pro-active and flexible attitude, sense of urgency and excellent collaboration skills are required
- Strong critical thinking skills and a strong scientific knowledge in toxicology, pathology, and drug metabolism/pharmacokinetics, and an ability to apply this knowledge to influence development programs are preferred
- Experience with in vivo gene therapy, ocular, and/or biologics toxicology studies is preferred
Johnson & Johnson is an Affirmative Action and Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
